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Perit Dial Int 27(Supplement_2): 21-26
2007
© 2007 International Society for Peritoneal Dialysis
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Part 1: PD Development and Enhancement of PD Programs

TELEMEDICINE SYSTEM FOR PATIENTS ON CONTINUOUS AMBULATORY PERITONEAL DIALYSIS

Hidetomo Nakamoto

Department of Nephrology, Saitama Medical University, Saitama, Japan

Correspondence to: H. Nakamoto, Department of Nephrology, Saitama Medical University, 38 Morohongo, Moroyamamachi, Iruma-gun, Saitama 350-0451 Japan. E-mail: nakamo_h{at}saitama-med.ac.jp


    ABSTRACT
 TOP
 ABSTRACT
 PATIENTS AND METHODS
 DISCUSSION
 CONCLUSIONS
 REFERENCES
 

Over recent decades, rapid progress in information and telecommunications technology has led to the application of these technologies in the medical field. In 1999, we reported on a telemedicine system (version 1.0) that used an automated peritoneal dialysis machine to collect data on patients with end-stage renal disease. After 2002, we focused on using cellular telephones in a new telemedicine system (version 2.0) to monitor patient data at home, including blood pressure (BP), heart rate, body weight, urine volume, and blood glucose. By 2003, we had developed a fully automatic system called I-converter (version 3.0) to collect data from a fully automatic device and send it via cellular telephone. After the fully automatic device measures a patient's BP, I-converter sends the data directly to the main server in our central data center. That server is directly connected to Web site by application service provider (ASP) technology. Recently, to make the system simpler, we developed a new version called D-converter (version 4.0). The telephone used in this new system is a Personal Handy-phone System (PHS). The PHS has several advantages: high-speed data transmission, low power output, little electromagnetic interference with medical devices, and easy locating of patients. The D-converter system uses a small computer and a PHS card called a Dopa card.

Our telemedicine systems monitor continuous ambulatory peritoneal dialysis (CAPD) patients at home. For elderly and handicapped patients, these systems are very advantageous because they reduce visits to the outpatient clinic. In addition, data can be monitored at the patient's home in real time. The present paper reports our recent advances in telemedicine systems for CAPD patients.

KEY WORDS: Telemedicine; CAPD; application service provider; ASP; cellular telephone.

Developments in information technology have been used to great advantage in many fields, including manufacturing, communications technology, network businesses, and medicine. Computer-assisted activity in medicine is increasing in several areas, perhaps most broadly in nephrology and dialysis because of the special characteristics of the population: numbers, complexity, long follow-up, and high cost (1).

Continuous ambulatory peritoneal dialysis (CAPD) is one treatment available for end-stage renal disease (ESRD) patients. In Japan, the proportion of patients treated with CAPD is very low, despite some reports that CAPD has certain benefits: lower mortality, lower cost, and better quality of life (26). The main factors that have negatively affected the development of CAPD in Japan are the rapid proliferation of renal units and the appearance of encapsulating peritoneal sclerosis, a serious complication for long-term CAPD patients (4). In addition, CAPD is home dialysis system, and patients must do everything themselves, including solution exchanges, catheter exit-site care, and record-keeping. Almost all CAPD patients have had some troubles with therapy at home during their CAPD life.

Because patients perform their own treatment, safety considerations require that all equipment be failsafe. Safe, easy-to-operate equipment and suitable training may allow patients and relatives to carry out treatments that are usually restricted to medical staff, but a medical support system for these CAPD patients is necessary for backup. A telemedicine system is an effective way of monitoring patient data at home, including blood pressure (BP), heart rate (HR), body temperature, body weight, urine volume, and exercise levels in ESRD patients. The telemedicine system described in the present paper supports our CAPD outpatients at home.


    PATIENTS AND METHODS
 TOP
 ABSTRACT
 PATIENTS AND METHODS
 DISCUSSION
 CONCLUSIONS
 REFERENCES
 
VERSION 1.0: TELEMEDICINE FOR HOME AUTOMATED PERITONEAL DIALYSIS
In 1999, we developed a telemedicine system (version 1.0) to monitor a 90-year-old woman undergoing automated peritoneal dialysis (APD) with a JMS system (PD mini: JMS, Tokyo, Japan) at home (7). Figure 1 shows the system, which consists of two major components: a data transport system and a view–send system (video conferencing). At any time, we could obtain patient data directly from APD system using the data transport system. Using video conferencing, we could talk with the patient face-to-face.


Figure 1
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Figure 1 — Version 1.0 telemedicine system connected to an automated peritoneal dialysis (APD) machine (PD mini: JMS, Tokyo, Japan). The two main components of this system were the data transport component and the view–send (video conferencing) component. TV = television; CO = patient's computer; Scale = weight scale (directly connected to APD system); Host CO = hospital computer.

 
At the hospital end, the system consisted of a host computer, a video camera, and an Internet connection. At the patient end was the APD system, a television with set-top box, a video camera, and a telephone connection. The equipment at the two ends was connected by the NTT telephone network (Nippon Telephone and Telegraph, Tokyo, Japan). No Internet connection or provider was involved. We could connect directly to the APD system at the patient's home and obtain all the data—including BP, HR, ultrafiltration volume (UFV), and body weight—directly every day. Furthermore, we could directly change the APD system schedule and the dose and times of the CAPD solution exchanges. In 1999, no broadband network system was available in Japan, and so the speed of the video-conferencing system was very slow during the daily discussions between patients and medical staff.

The system was made very simple so that the original patient did not need to use a computer. The number of additional patients using this system was small because of the high cost (US$30,000). However, once installed, maintenance costs for the system were very small. Retrieving the data from APD system cost only 10 cents daily (telephone charges).

VERSION 2.0: TELEMEDICINE USING A CELLULAR TELEPHONE
To popularize telemedicine for all CAPD patients, cost reduction and miniaturization were imperative. We began by focusing on cellular telephones for a new version of our telemedicine system.

In 2002, we developed a new system version that used a cellular telephone and application service provider (ASP) technology to monitor patient data (8). Software for the telemedicine system was downloaded directly from an I-mode site (a system developed in Japan) constructed by NTT DoCoMo (Tokyo, Japan). The I-mode site could be contacted by cellular telephone over the Internet. When the software was downloaded from the I-mode site to the cellular telephone, the telephone was able to act as a sort of personal data assistant, collecting and monitoring data (Figure 2).


Figure 2
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Figure 2 — Version 2.0 telemedicine system using a cellular telephone. The two main components of this system were a data collection and monitoring system and an electronic medical-record sharing system (Web site) managed by application service provider (ASP) technology.

 
Using the cellular telephone as data collection device was easy. For each patient, all data collected—BP, body weight, UFV, and urine volume—were sent directly to the main server in the NTT DoCoMo data center, where they accumulated. The server was directly connected by ASP to a Web site. Any time and anywhere, each patient could review his or her personal data in graph form using the cellular telephone or a computer to visit the Web site. The averages of the various data points were calculated and displayed on the Web site. Abnormal data were sent directly to office of the patient's physician, where the host computer would sound an emergency signal (alarm system). Each patient's cost for using this system was just US$3.00 or less per month.

This version of the telemedicine system held big advantages for our CAPD patients, especially the ones who were elderly or handicapped. Moreover, it allowed all CAPD patients and all hospitals in Japan to be networked.

Monitoring Data by Computer on the Web: Any time that patients want to check their data, they can use a computer to access the Web site. At the site, they can monitor the raw data or the averages and graphs. All data from the patients are collected by the ASP system and calculated by computer. If members of the medical staff want to see patient data, they can also access the Web site. If data from hypertensive patients suggests trouble, the medical staff receive emergency signals by cellular telephone or computer. They can then call the patient for a consultation by cellular telephone.

VERSION 3.0: I-CONVERTER DATA COLLECTION SYSTEM WITH CELLULAR TELEPHONE
Patients on CAPD usually recorded their data in a notebook. Version 2.0 of our telemedicine system used a computer system instead of a notebook. Version 2.0 was good for monitoring patient data at home, but patients still had to input the data by themselves. Some of the patients using that system suggested that the system should be able to download the necessary data from automated devices such as the BP monitor, glucose monitor, scale, and so on.

To move data from a fully automatic device to the cellular telephone, we developed a new data collection system (9) called I-converter ("Internet-mediated converter"). Figure 3 shows this system advance. After the patient measures his or her BP with a fully automatic device [HEM-705IT: Omron Life Science, Tokyo, Japan (10)], I-converter is connected between the device and the cellular telephone. When the connection is complete, a green signal switches on. The user then pushes the I-converter button, and the data (BP, HR, and time) are downloaded directly into the memory of the cellular telephone (Figure 3).


Figure 3
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Figure 3 — Version 3.0 telemedicine system using I-converter data collection technology. Data is collected from a fully automated blood-pressure measurement device (HEM-705IT: Omron Life Science, Tokyo, Japan) to a cellular telephone. The I-converter connects the two devices.

 
The data thus collected are sent directly to the main server at our data center. All data from each patient are accumulated in the server, which is directly connected to a Web site by ASP technology. Any time and anywhere, CAPD patients can access the I-system Web site. All patients can use a cellular phone or computer to monitor changes in their averaged or graphed data at the Web site.

VERSION 4.0: D-CONVERTER DATA COLLECTION SYSTEM WITH PHS
Many patients were now using our system to send data to the server, but only a small number of patients were using the cellular telephone to check the data. More often, they were using a computer to check the Web site. Also, almost all patients were using the telemedicine system only at home. To make the system easier, we developed a new version called D-converter ("Dopa card–mediated converter"). The type of telephone used in this new system version is the PHS, a system developed in Japan that uses the NTT telephone network. The PHS has several advantages: high-speed data transmission, low power output, little electromagnetic interference with medical devices, and ease in locating patients.

The D-converter system uses a small computer and PHS card, and operates in almost the same way that I-converter does, but no cellular telephone is involved (Figure 4). D-Converter can connect directly to the automated BP monitoring device—or to the automatic glucose checker (Onetouch Ultra: J&J, Tokyo, Japan), the automatic scale (Omron HBF-354IT: Omron Life Science), and the pedometer (Omron HJ-720IT: Omron Life Science)—and download the data, sending the data directly to the server in our data center. When patients want to check their data, they can use a computer to visit the Web site.


Figure 4
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Figure 4 — Version 4.0 telemedicine system using D-converter (JMS DC-100: JMS, Tokyo, Japan) data collection technology. The D-converter comprises a small computer and Personal Handy-phone System (Dopa) card (NTT, Tokyo, Japan). The D-converter is similar to the I-converter, but no cellular telephone is required. After measurements using fully automated devices [blood pressure (HEM-705IT monitor: Omron Life Science, Tokyo, Japan), blood glucose (One Touch Ultra monitor: J&J, Tokyo, Japan), body weight (Omron HBF-354IT scale: Omron Life Science), and exercise (Omron HJ-710IT pedometer: Omron Life Science)] are taken, the D-converter is connected to download all the data from the devices. Then, at the push of a button, all data are sent directly to the main server in the NTT data center. Patients can view their data by using a computer to visit a Web site managed by application service provider (ASP) technology.

 

In 2006, some CAPD patients in Japan were using this latest telemedicine system to monitor their BP, HR, body weight, blood glucose, and exercise level. Many of our patients with hypertension, diabetes, metabolic syndrome, and nephritis were using the system.


    DISCUSSION
 TOP
 ABSTRACT
 PATIENTS AND METHODS
 DISCUSSION
 CONCLUSIONS
 REFERENCES
 
In 2000, we reported the first CAPD telemedicine system that connected to an APD system (7). In the case of the APD system, data are collected about the state of both the patient and the APD machine, providing feedback information. That system held great advantages for all patients using the APD system—but only for the APD patients. At our hospital, only 20% of peritoneal dialysis patients were using APD. Many of our CAPD patients wanted to use this kind of system but could not.

In 2002, we tried to develop a system that all CAPD patients could use, because we wanted to make telematic monitoring services available to support all uremic patients. The system we foresaw needed to be simple and very easy to manage, even for elderly and handicapped patients. For ease of use, we constructed a system that used a cellular telephone as a data collection device. All data were collected by cellular telephone and sent directly to a server in the NTT DoCoMo data center (8).

Earlier, trials of a telemedicine system for ESRD had been reported. Moncrief and Sorrels (11,12) reported the Texas Telemedicine Project (TTP) in Giddings, Texas, which was designed to evaluate the economic practicality of delivery of medical care through bidirectional interactive video. But that project was designed for patients on hemodialysis, not on CAPD.

From March 1990, dialysis patients were monitored and primary care was delivered through the electronic medium. The TTP offered an avenue for the physician participants to explore the best delivery system for successfully deploying telemedicine in the practice of nephrology. The patients quickly became comfortable with interactive health care delivery, and they preferred it as a means of receiving primary care and continuous physician monitoring during dialysis treatments. From this large-scale project, it was concluded that telematic health care delivery would be successful if the patient–physician relationship were to closely mimic face-to-face contact (11,12).

This report was the first of a telemedicine system used for a large number of dialysis patients. Recently, other publications have reported the efficacy of a telemedicine system to monitor home hemodialysis (13,14). Computer-based videoconferencing systems interface with dialysis machines and clinical information systems to create a paperless medical record, which includes screen captures of vascular access images and a database of dialysis parameters, among other data.

Telemedicine for the care of dialysis patients is being studied and used routinely in centers throughout the world (1114); however, telemedicine to monitor home CAPD patients is little reported. Recently, Gallar et al. (15) reported the usefulness of a telemedicine system for 18 months of follow-up in stable patients in CAPD. Daily costs after installation of the system were low, and patients and medical personal saved time, the renal unit saved on physical space, and everyone saved on transportation. Gallar's report and ours demonstrates that a telemedicine system holds big advantages for the management of CAPD outpatients.

We speculate that, in future, telemedicine systems will come to be used more routinely in medicine. We believe that our telemedicine system provides ESRD patients on CAPD with supervised autonomy.


    CONCLUSIONS
 TOP
 ABSTRACT
 PATIENTS AND METHODS
 DISCUSSION
 CONCLUSIONS
 REFERENCES
 
We developed a new version of our telemedicine system that monitors the condition of CAPD patients by cellular phone and Web site. The system has great benefits for these patients. The system could potentially be expanded into a networked system for patients and medical staff worldwide. The system helps to maintain CAPD patients in good condition, especially elderly and handicapped patients, who benefit by being managed at home.


    REFERENCES
 TOP
 ABSTRACT
 PATIENTS AND METHODS
 DISCUSSION
 CONCLUSIONS
 REFERENCES
 

  1. Formica M, Quarello F, Stramignoni E, Pozzato M, Forneris G, Iadarola GM, et al. Informatics support and teledialysis [Italian]. Minerva Urol Nefrol 1994;46 : 11-16.[Medline]
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  4. Diaz–Buxo JA, Lowrie EG, Lew NL, Zhang H, Lazarus JM. Quality-of-life evaluation using Short Forum 36: comparison in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis2000; 35:293 -300.[Medline]
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  6. Moeller S, Gioberge S, Brown G. ESRD patients in 2001: global overview of patients, treatment modalities and development trends. Nephrol Dial Transplant 2002;17 : 2071-6.[Free Full Text]
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  15. Gallar P, Gutierrez M, Ortega O, Rodriguez I, Oliet A, Herrero JC, et al. Telemedicine and follow up of peritoneal dialysis patients [Spanish]. Nefrologia 2006;26 : 365-71.[Medline]



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