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REVIEWS AND ORIGINAL ARTICLES |
Department of Renal Medicine, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden
Correspondence to: Anders Tranæus, Karolinska Institute, Department of Nephrology, K 56, Huddinge University Hospital, S-141 86 Sweden.
This study of 228 episodes of peritonitis occurring during a total
observation time of 2365 treatment months over a six-year period in a
uniformly selected, trained, and treated continuous ambulatory peritoneal
dialysis (CAPD) population (N = 124) showed the following major
findings: 1) the risk of developing peritonitis was 55% within the first year
and 89% within the first three years on CAPD; 2) high age (≥60 years)
and year of CAPD start were risk factors for peritonitis; 3) neither sex,
diabetes, or hypoalbuminemia were found to be risk factors for peritonitis; 4)
the year of start, but neither the degree of severity, nor the time of the
first episode affected the risk of developing a second episode of peritonitis;
5) no specific characteristics were identified in patients with the highest
mean peritonitis incidence or in the patients without peritonitis; 6) in 27%
of all episodes, turbidity of the dialysate was the only clinical finding; 7)
the proportion of asymptomatic episodes was lower in patients ≥ 60
years; 8) the degree of clinical severity of peritonitis was not statistically
influenced by the number of previous episodes; 9) the cause of peritonitis was
established in only 26% of all cases; and 10) no statistical association was
found between the cause of peritonitis and p atient characteristics.
KEY WORDS: Risk factors; pathogenesis; peritonitis.
Received 12 April 1988; accepted 25 May 1988.
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