PDI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Perit Dial Int 8(3): 199-202 1988
© 1988 International Society for Peritoneal Dialysis
This Article
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bog, H. J.
Right arrow Articles by Beelen, R. H. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Bog, H. J.
Right arrow Articles by Beelen, R. H. J.

REVIEWS AND ORIGINAL ARTICLES

Peritoneal Macrophages in Short Dwell Time Effluent Show Diminished Phagocytosis

Harm J. Bog, Klaag Vlaanderen1, Jan. van der Meulen1, Jog C. de Veld, Liem P. Oe1 and Robert H. J. Beelen2

Departments of Cell Biology,1 Nephrology, and2 Haemotology, Medical Faculty and University Hospital, Free University, Amsterdam, The Netherlands

Correspondence to: H.J. Bos, Dept. Cell Biology, Medical Faculty, Free University, P.O. Box 7161, NL-1007 MC Amsterdam, The Netherlands.

We investigated the effect of different i.p. dwell times of dialysis fluid on the composition and phagocytic capacity of the peritoneal cells. We examined dialysate after 1.5 and 15 h dwell time in 10 continuous cyclic peritoneal dialysis (CCPD) patients and after 8 h dwell time in 14 continuous ambulatory peritoneal dialysis (CAPD) patients. There was no significant difference in viability, composition, and Fc receptor positive cells among the peritoneal cells in the studied effluents of CCPD and CAPD patients. However, the yield of peritoneal cells and the phagocytic capacity of IgG-coated sheep red blood cells ([lgG]SRBC) by peritoneal macrophages in 1.5 h dwell time dialysate was significantly decreased when compared with 15 h dwell time dialysates. In addition, the total phagocytic capacity of peritoneal cells in 1.5 h dwell time dialysate is dramatically decreased when compared with the 15 h dwell time dialysate and 8 h dwell time dialysate of CAPD patients. These findings must be taken in consideration by performing three rapid exchanges after the diagnosis of a peritonitis.

KEY WORDS: Continuous cyclic peritoneal dialysis (CCPD); peritoneal macrophages; phagocytosis; peritonitis.

Received 12 April 1988; accepted 25 May 1988.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Multimed Inc. logo
Copyright © 1988 by Multimed Inc.