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REVIEWS AND ORIGINAL ARTICLES |
Division of Nephrology, Toronto Western Hospital, University of Toronto, Ontario, Canada
Correspondence to: Hugh R. Brady, Division of Nephrology, Toronto Western Hospital, University of Toronto, ontario, Canada M5T 2S8.
Continuous ambulatory peritoneal dialysis (CAPD) patients are not
considered to be at increased risk of infection after transplantation when
compared to other renal transplant recipients. This article describes two
patients who developed bowel erosion and life-threatening peritonitis
following irritation from a dormant, indwelling peritoneal catheter. In both
cases, the classical signs of peritonitis were masked by immunosuppressive
therapy. In one patient, the catheter was removed, but she died of fecal
peritonitis and sepsis. The second patient, who was taken to the operating
room for laparotomy once peritonitis was diagnosed, survived; he required
segmental resection and appendectomy because of multiple bowel erosions. As a
result of this experience, we suggest that the peritoneal catheter be removed
as early as possible after transplantation once renal function has been
established. Furthermore, we believe that peritonitis developing in patients
with dormant indwelling peritoneal dialysis catheters should have a prompt
exploratory laparotomy to rule out perforation, because in an immunosuppressed
host this condition may be rapidly fatal.
KEY WORDS: Continuous ambulatory peritoneal dialysis (CAPD) complications; bowel perforation; renal transplantation; immunosuppressive therapy; peritonitis.
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