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REVIEWS AND ORIGINAL ARTICLES |
From the Department of Nephrology, Spedali Civili, Brescia, Italy.
During 1981-1984, at our center 6/75 patients on CAPD and 1/86 on HD
demonstrated a recovery of renal function. This and the observation that
diuresis was maintained on CAPD, led us to study urine output (UO) and
creatinine clearance (CrCI) in 41 patients on CAPD (CAPDp) and 45 on HD (HDp)
without the use of diuretics. CAPDp had a decline in diuresis from 1201
± 379 mI/day to 731 ± 572 (p < 0.01). HDp diuresis
decreased from 1233 ± 439 to 438 ± 568 (p < 0.01).
Creatinine clearance: HDp 5.8 ± 1.6 ml/min before, 1.3 ±
1.5 after; CAPDp 6.4 ± 2.0 before, 3.9 ± 2.9 after.
After one year, HDp showed a significant drop in diuresis; three years passed
before CAPDp had significant drop. Patients with glomerulonephritis showed the
same trend on HD and CAPD. CAPDp with interstitial nephropathy had a smaller
mean annual decrease in UO and CrCI, compared to HDp. CAPDp with
nephroangiosclerosis showed less decrease in diuresis compared to HDp. These
data confirm that, compared to HD, CAPD treatment main tains residual renal
function even in patients not using diuretics, and suggest that CAPD is a
treatment of choice for those considered likely to recover renal function.
KEY WORDS: Residual renal function; urine output; residual creatinine clearance; diuresis.
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