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Perit Dial Int 5(2): 109-111 1985
© 1985 International Society for Peritoneal Dialysis
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REVIEWS AND ORIGINAL ARTICLES

SURFACE-ACTIVE MATERIAL IN PERITONEAL EFFLUENT OF CAPD PATIENTS

Gordon R. Grahame, Mark G. Torchia, Katherine A. Dankewich and Ian A. Ferguson

From the Dialysis Unit, Departments of MedicIne and Surgery, St. BonIface General Hospital and the University of Manitoba.

The dialysis effluent of patients on continuous ambulatory peritoneal dialysis contains a surface-active material (SAM). This is composed of phospholipids; on thin-Iayer chromatography, this appears to be mainly phosphatidylcholine. Similar to the material described by Hills on the pleural surfaces of dogs (4), this SAM markedly reduces surface tension and promotes water repellency. The authors postulate that it may playa role in ultrafiltration and in the prevention of infection in CAPD patients.

KEY WORDS: CAPD; Surface active material; Peritoneum.






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