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A CROSS SECTIONAL ASSESSMENT OF SERUM VITAMIN D AND TRIGLYCERIDE CONCENTRATION IN A CAPD POPULATION

From The University of Missouri Health Science Center, Room M472, 1 Hospital Drive, Columbia, Missouri 65212, U.S.A.

A cross sectional analysis of 41 patients on continuous ambulatory peritoneal dialysis (CAPD) for six to 54 months (mean, 21.7) showed that 58.5% and 19.5% had low levels of 1,25-(OH)2 vitamin D and 25-OH vitamin D respectively. C-terminal and N- terminal parathyroid hormone (PTH) levels were elevated in 85 and 75%, respectively. N-terminal PTH correlated (r -0.31, p < 0.05) with serum inorganic phosphorus, but not with vitamin D levels. Triglyceride and cholesterol concentrations were elevated in 76% and 19%; HDL cholesterol was low in 37%. Except for PTH levels, none of the other above measurements correlated with time on CAPD. The findings suggest that most CAPD patients have low 1,25(OH)2 vitamin D and elevated PTH and triglyceride serum concentrations. More study should be made concerning the clinical significance of and proper therapeutic interventions in these circumstances.

KEY WORDS: Vitamin D; Cholesterol; Triglycerides; Parathyroid Hormone.

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