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Perit Dial Int 30(1): 95-98
2010
© 2010 International Society for Peritoneal Dialysis
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Clinical

INFLUENCE OF THE PRECEDING DWELL TIME ON THE PERITONEAL EQUILIBRATION TEST WITH 3.86% GLUCOSE SOLUTION IN AUTOMATED PERITONEAL DIALYSIS

Trijntje Cnossen1, Charles Beerenhout2, Watske Smit3, Constantijn Konings4, Jeroen Kooman1, Karel Leunissen1 and Raymond T. Krediet5

Internal Medicine,1 Maastricht UMC, Maastricht; Internal Medicine,2 Maxima Medical Center, Veldhoven; Nephrology,3 Academic Medical Center, University of Amsterdam, Amsterdam; Internal Medicine,4 Catharina Hospital, Eindhoven; and Renal Unit,5 Academic Medical Center, Amsterdam, The Netherlands

Correspondence to: T. Cnossen, Internal Medicine, Maastricht UMC, Postbus 5800, Maastricht 6202AZ, The Netherlands. nynke.cnossen{at}mumc.nl

{diamondsuit} Objective: The peritoneal equilibration test (PET) using 3.86% glucose solution is preceded by a long dwell with 3.86% glucose solution. A point of concern in patients treated with automated peritoneal dialysis (APD) is the influence of the preceding short nightly dwells on the results of a standardized PET. The aim of the study was to compare net ultrafiltration, small solute transport, sodium sieving, and solute transport type between a PET preceded by a long night dwell and one preceded by short (APD) dwells.

{diamondsuit} Patients and Methods: 13 stable APD patients (mean age 60 ± 15 years; mean duration of peritoneal dialysis 31 ± 15 months) underwent 2 PETs: 1 preceded by short nightly dwells (PET A) and 1 preceded by a long night dwell (PET B).

{diamondsuit} Results: Both PETs were performed within a mean period of 8 (range 5 – 11) days. Mean total ultrafiltration of PET A was 626 ± 218 mL and PET B was 644 ± 223 mL (NS). The 4-hour results of both tests for dialysate-to-plasma (D/P) ratios of creatinine and urea, Dt/D0 ratios of glucose, and the dip in D/P sodium (sodium sieving) were similar. Classification of transport categories was identical for 10 of 13 patients.

{diamondsuit} Conclusion: In APD, the preceding dwell time of a 3.86% glucose PET does not influence fluid transport, solute transport, or transport type.

KEY WORDS: Peritoneal equilibration test; dwell time; solute transport; sodium sieving; automated peritoneal dialysis.

Received 24 March 2009; accepted 15 April 2009.






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