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Perit Dial Int 3(3): 126-127 1983
© 1983 International Society for Peritoneal Dialysis
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REVIEWS AND ORIGINAL ARTICLES

INTRAPERITONEAL INSULIN CANNOT CORRECT THE HYPERLIPIDEMIA OF CAPD

Stephen F. Beardsworth*, Henry J. Goldsmith** and Brent R. Stanbridge***

* Merseyside Association for Kidney Research** Regional Renal Unit *** Dept. Clinical Chemistry Sefton General Hospital, Smithdown Road, Liverpool 15, ENGLAND

We have investigated the effect of the administration of small doses of intraperitoneal insulin (mean 2.7 ± 1.45 u/L) on the hyperlipidemia associated with continuous ambulatory peritoneal dialysis (CAPD) in nine non-diabetic patients. Despite significant lowering of both fasting (6.21 ± 0.9 -> 4.2 ± 0.5 mmoI/L) and postprandial (9.74 ± 1.1 -> 7.4 ± 1.06 mmol/L) blood glucose levels, we saw no effect on serum total cholesterol, triglycerides or B lipoproteins.






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