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RENAL OSTEODYSTROPHY IN PATIENTS MAINTAINED ON CAPD FOR MORE THAN THREE YEARS

From the Departments of Medicine, Radiology and Pathology, Toronto Western Hospital and University of Toronto.

Studies of renal osteodystrophy in patients maintained on CAPD for short periods have shown conflicting results. The present study reports on the status of renal osteodystrophy in 27 patients maintained on CAPD for over three years. Ten men and 17 women with a mean age of 49.5 years were on CAPD for a mean of 45 months. Dialysate calcium was 6 mg%. Oral dietary calcium intake for all the patients was low (= 500 mg/day). AI(OH)3' Vit. D and/or 1,25(OH)2D3 were prescribed to maintain serum calcium and phosphorus at normal levels. Patients were divided into two groups according to the radiological findings at the beginning of treatment. Group A (10 patients) included those who had no subperiosteal resorption (SPR) and Group B (17 patients) those with SPR at the initiation of CAPD. In Group A, SPR grade remained normal in eight patients and progressed in two. In Group B, SPR remained unchanged or increased in 14 while it improved in the remaining three.

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