|
|
||||||||
Part 4: Metabolic Syndrome and Nutrition in PD |
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, PR China
Correspondence to: P.K.T. Li, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, PR China. philipli{at}cuhk.edu.hk
Metabolic syndrome (MetS) occurs in about 50% of peritoneal dialysis
(PD) patients. It encompasses a cluster of major risk factors for
cardiovascular diseases. A modified National Cholesterol Education Program
Third Adult Treatment Panel guideline for the diagnosis of MetS in PD patients
has been proposed. Preliminary data suggest that PD patients with MetS in our
cohort have an increased risk of cardiovascular mortality. The proinflammatory
effects of adipose tissue are one of the reasons for poor outcome in obese PD
patients. Lifestyle modification, including appropriate dietary restriction
and exercise, especially reduction of fat mass in obese patients, has been one
of the major areas proposed for managing patients with MetS. Individual
therapeutic trials are treating hyperglycemia, hypertension, and dyslipidemia
in dialysis patients. Evidence in PD patients that interventions targeting
MetS can improve outcomes is still lacking. Large-scale studies with data on
the clinical outcome for MetS intervention in PD patients are needed.
KEY WORDS: Metabolic syndrome.
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |