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Clinical |
Renal Division,1 Department of Internal Medicine, Saint Mary's Hospital, Lo Tung; Renal Division,2 Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine; Department of Health,3 Taipei Hospital, Executive Yuan, Taiwan
Correspondence to: T.S. Chu, Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Road, Taipei 100, Taiwan. tschu{at}ntu.edu.tw
Background: There are no Taiwanese publications and
only a few Asian publications on the long-term outcome of peritoneal dialysis
(PD) patients. The aim of this study was to evaluate the outcome of PD
patients in Taiwan during a 7-year follow-up period.
Patients and Methods: This study enrolled 67 patients
(23 males, mean age 46.2 ± 14.5 years) on maintenance PD. We
administered the Short-Form questionnaire on 30 September 1998 and recorded
major events and outcomes until 30 September 2005. We compared differences in
initial parameters between groups categorized by PD patient survival and PD
technique survival. Causes of mortality and transfer to hemodialysis were
determined. PD patient and PD technique survival rates were measured and risk
factors for patient mortality and PD technique failure were analyzed.
Results: Those in patient survival or PD technique
survival groups had lower mean age (p < 0.001 and 0.018
respectively) and higher serum albumin level (p = 0.015 and 0.041
respectively) compared to those that died or failed PD. The 7-year patient
survival rate was 77% and the PD technique survival rate was 58%. The
independent predictors for PD technique failure included lower Mental
Component Summary scores [hazard ratio (HR) = 0.85, p = 0.031] and
diabetes mellitus (HR = 4.63, p < 0.001), whereas lower serum
albumin level (HR = 0.22, p = 0.031), lower Physical Component
Summary scores (HR = 0.67, p = 0.047), and presence of diabetes
mellitus (HR = 5.123, p = 0.009) were the independent predictors for
patient mortality.
Conclusion: For our PD patients, both patient and
technique survival rates are good. Better glycemic control, adequate
nutrition, and enhancement of health-related quality of life are all of
potential prognostic benefit.
KEY WORDS: Follow-up; survival rate; health-related quality of life.
Received 29 August 2007; accepted 2 September 2008.
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