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Perit Dial Int 28(Supplement_3): 167-171 2008
© 2008 International Society for Peritoneal Dialysis
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Part 7: Immunodysfunction and Peritonitis in PD

INFECTIOUS COMPLICATIONS IN CHRONIC DIALYSIS PATIENTS

Robert N. Foley

Chronic Disease Research Group, Minneapolis, Minnesota and University of Minnesota, Minneapolis, Minnesota, U.S.A.

Correspondence to: Robert N. Foley, Chronic Disease Research Group, 914 South 8th Street, Suite S-430, Minneapolis, Minnesota 55404 U.S.A.
RFoley{at}cdrg.org

Surprisingly little formal research has examined the issue of major bacterial infections in chronic dialysis patients. This is a surprising situation, because uremia is a classic state of immune hyporesponsiveness, and infection rates are believed to be several times higher in dialysis populations than in age-matched segments of the general population. The present paper focuses on the clinical epidemiology of major bacterial infections in dialysis patients, associations between bacterial infections and cardiovascular disease, and interventions aimed at averting these infections.

KEY WORDS: Pneumonia; septicemia; cardiovascular mortality.






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