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Part 6: Peritoneal Transport |
Department of Materials Science and Engineering, College of Engineering, Shonan Institute of Technology, Fujisawa, Japan
Correspondence to: Akihiro C. Yamashita, Department of Materials Science and
Engineering, College of Engineering, Shonan Institute of Technology, 1-1-25
Tsujido-Nishikaigan, Fujisawa, Kanagawa 251-8511
Japan.
yama{at}la.shonan-it.ac.jp
Kinetic models have been used in both hemodialysis (HD) and peritoneal
dialysis (PD) therapies. Because many different theoretical models are
available, users should choose a model that suits the purpose of their
studies. In general, simple models are useful for clinical investigations and
research; rigorous models may be available with the use of computers. Several
commercial software packages with rigorous models specifically designed for PD
are also useful for analyzing patient data and for constructing prescriptions.
Although the overall mass transfer area coefficient (MTAC) is a parameter for
diffusion transport, it may become a useful tool for predicting peritoneal
ultrafiltration by defining a new "index for peritoneal diffusive
selectivity" (IPDS), the ratio of the MTACs for urea and creatinine.
Kinetic models are especially useful in treatments with relatively complex
prescriptions such as combined PD and HD ("complementary")
therapy, sample calculations of which are discussed.
KEY WORDS: Overall mass transfer area coefficient (MTAC); Pyle-Popovich model; three-pore model; index for peritoneal diffusive selectivity (IPDS); combined PD and HD (complementary) therapy.
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