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INVITED REVIEWS |
Indiana University School of Medicine and Roudebush VAMC, Indianapolis, Indiana, U.S.A.
Correspondence to: S.M. Moe, Indiana University School of Medicine, 1001 W. 10th Street, OPW 526, Indianapolis, Indiana 46202 U.S.A. smoe{at}iupui.edu
The definition, evaluation, and classification of the mineral
abnormalities and bone disease in chronic kidney disease (CKD) should
encompass all three clinical components:
This principle was discussed at a Kidney Disease: Improving Global
Outcomes consensus conference, resulting in a recognition of the shortcomings
of the current classification and a recommendation for the development of new
terminology. The recommendation was that the term "renal
osteodystrophy" be used exclusively to define the bone pathology
associated with CKD. The many clinical, biochemical, and imaging abnormalities
that have heretofore been identified as correlates of renal osteodystrophy
should be defined more broadly as a clinical entity or syndrome called
"chronic kidney disease – mineral and bone disorder." The
hope is that this new terminology will enhance communication and facilitate
research worldwide.
KEY WORDS: Mineral bone disorder; renal osteodystrophy; calcium; phosphorus; parathyroid hormone; vascular calcification; bone.
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