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Perit Dial Int 28(Supplement_2): 20-25 2008
© 2008 International Society for Peritoneal Dialysis
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INVITED REVIEWS

VASCULAR CALCIFICATION IN PERITONEAL DIALYSIS PATIENTS

Adriano Luiz Ammirati1, Rosa Maria Affonso Moysés2 and Maria Eugênia Canziani1

Federal University of São Paulo,1 Nephrology Division, and University of São Paulo,2 Nephrology Division, São Paulo, Brazil

Correspondence to: M.E.F. Canziani, R. Pedro de Toledo, 282, São Paulo, SP 04039-000 Brazil. dialisefor{at}uol.com.br

Vascular calcification (VC) is being recognized as a common complication at all stages of chronic kidney disease, particularly in patients on dialysis. Traditional and nontraditional cardiovascular risk factors both appear to be involved in the development of VC in this population. Although few studies focusing exclusively on peritoneal dialysis (PD) patients are available, some data support the view that VC constitutes an independent prognostic marker of morbidity and mortality in the PD population. In this review, we discuss the potential pathophysiologic pathways of VC in PD patients, and we examine the relevant clinical data.

KEY WORDS: Vascular calcification; coronary artery calcification; CKD.






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