HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Moossavi, S. Articles by Burkart, J. Search for Related Content PubMed Articles by Moossavi, S. Articles by Burkart, J.

Comparison of Mean Kt/V and Anuric Kt/V in Adult Peritoneal Dialysis Patients Based on Weight

Wake Forest, Winston Salem, North Carolina, USA

Objective: To compare the clinical outcomes of mean Kt/V, anuric Kt/V, time to first infection, time to first catheter complication, and survival at 1 year in adult peritoneal dialysis (PD) patients based on weight.

Methods: We performed an observational cohort study of all incident adult PD patients at an academic outpatient dialysis clinic from January 2004 to December 2006. Comparison of mean Kt/V and anuric Kt/V between patients weighing less than 100 kg (Group 1) and those whose weight was equal to or more than 100 kg (Group 2). Infection was defined as exit-site infection, tunnel infection, and peritonitis.

Results: There were 138 incident PD patients during the study period (60 females, 78 males). Group 1 had 112 patients, 105 of whom were anuric. Patient weights ranged between 45.3 kg and 99.3 kg (median 75.2). One-year survival was 90.2%. Mean Kt/V 2.56 (standard deviation 0.71; minimum 0.97, maximum 4.38). Mean anuric Kt/V was 2.59 (min 0.97, max 4.38). Median time to first infection was 16.1 months, and median time to first catheter complication was 4 months. Group 2 (weight >100) had 26 patients of whom 23 were anuric. The weight ranges between 100.2 kg and 151.9 kg (median=108.8). One-year survival was 100%. Mean Kt/V was 2.18 (SD 0.50; min, 1.43 max 3.28). Mean anuric Kt/V was 2.24 (min 1.45, max 3.28). Median time to first infection was 9.2 months and median time to first catheter complication was 2.3 months.

Conclusions: Patients in both groups achieved a mean Kt/V at the recommended target Kt/V. One-year survival was not statistically different between the 2 groups (p=0.09). Group 2 (weight >100) had an earlier time to first infection and first catheter complication than Group 1 (weight <100 kg).

Copyright © 2007 by Multimed Inc.