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Clinical |
Children's Mercy Hospitals and Clinics, Kansas City, Missouri, USA
Correspondence to: B.A. Warady, Children's Mercy Hospitals and Clinics, 2401
Gillham Road, Kansas City, Missouri, 64108
USA.
bwarady{at}cmh.edu
Background: The peritoneal equilibration test (PET) is a
4-hour procedure that is recommended to be performed in children receiving
peritoneal dialysis to assist in prescription management. While a shortened
version of the PET has been used in adults and reliably characterizes
peritoneal membrane transport capacity, no similar experience with children
has been reported. Methods: Retrospective evaluation of 2-hour and 4-hour PET
data obtained from 20 children receiving chronic peritoneal dialysis in a
single center. Characterization of membrane transport capacity was based on
evaluation of serum and dialysate samples used to determine the
dialysate-to-plasma ratio (D/P) of creatinine and the ratio of dialysate
glucose to baseline dialysate glucose (D/D0). Patient values were
compared to pediatric reference data. Results: In all 20 patients, characterization of
peritoneal membrane transport capacity using 2-hour D/P and D/D0
results was identical to that determined using 4-hour data for the same
solute. While the creatinine- and glucose-based characterization was
discrepant in 14 of 20 patients, in only 1 case was the discrepancy of more
than a single transport category. Conclusion: These results support the accuracy of a short
PET in children, a procedure that should prove beneficial in terms of patient
and staff time.
KEY WORDS: Peritoneal equilibration test; pediatric.
Received 30 October 2006; accepted 6 February 2007.
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