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Clinical |
1 Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, Bellflower; 2 Research and Evaluation Department, Kaiser Permanente Southern California, Pasadena, California, USA
Correspondence to: J.H. Crabtree, Department of Surgery, Module 4400, Kaiser
Permanente Bellflower Medical Center, 9400 E. Rosecrans Avenue, Bellflower,
California 90706
USA.
John.H.Crabtree{at}kp.org
Objective: Guidelines for optimal peritoneal dialysis
access support both downward and lateral exit-site directions. Numerous
clinical reports support the superiority of downward exit sites but none
substantiate lateral configurations.
Methods: This prospective study compared infectious and
mechanical complications between 85 catheters with a preformed arcuate bend to
produce a downward exit site and 93 catheters with a straight intercuff
segment configured to create a lateral exit site.
Results: Kaplan-Meier survivals were not different for
time to first exit-site infection (p = 0.62), tunnel infection
(p = 0.89), or peritonitis (p = 0.38) for downward and
lateral exit-site directions. Poisson regression showed no differences in
rates (episodes/patient-year) of exit-site infection (0.26 vs 0.27, p
= 0.86), tunnel infection (0.02 vs 0.03, p = 0.79), peritonitis (0.42
vs 0.43, p = 0.87), or catheter loss (0.06 vs 0.09, p =
0.29) for downward and lateral exit sites. Kaplan-Meier analyses of
antibiotic-free intervals for exit-site (p = 0.94) and peritonitis
infections (p = 0.72) were not different for the two groups. There
was one case of catheter tip displacement with flow dysfunction in each group.
There were no pericatheter hernias or spontaneous cuff extrusions. Catheter
survival between groups was not different (p = 0.20).
Conclusions: Catheter types employing downward and lateral
tunnel-tract and exit-site configurations produce equivalent outcomes for
infectious and mechanical complications.
KEY WORDS: Tenckhoff catheter; swan neck catheter; exit-site infection; tunnel infection; peritonitis; cuff extrusion; catheter tip migration; catheter survival.
Received 21 February 2006; accepted 19 April 2006.
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