PDI 2009 ISDP LAC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Perit Dial Int 24(1): 65-67 2004
© 2004 International Society for Peritoneal Dialysis
This Article
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sepandj, F
Right arrow Articles by Olson, M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sepandj, F
Right arrow Articles by Olson, M
Peritoneal Dialysis International, Vol 24, Issue 1, 65-67
Copyright © 2004 by International Society for Peritoneal Dialysis

Articles

Minimum inhibitory concentration (MIC) versus minimum biofilm eliminating concentration (MBEC) in evaluation of antibiotic sensitivity of gram-negative bacilli causing peritonitis

F Sepandj, H Ceri, A Gibb, R Read, and M Olson

Department of Medicine, University of Calgary, Calgary, Alberta, Canada. fsepandj@shaw.ca

OBJECTIVE: Minimum inhibitory concentration (MIC) and minimum biofilm eliminating concentration (MBEC) results were compared to determine changes in the pattern of antibiotic sensitivity of gram-negative bacilli from the planktonic to the biofilm phase of growth. METHODOLOGY: The MIC and MBEC assays were conducted on stored isolates obtained from patients presenting with peritoneal dialysis-related gram-negative peritonitis with Escherichia coli or Pseudomonas. RESULTS: The antibiotic sensitivities of planktonic organisms tested by the MIC assays were significantly higher than the antibiotic sensitivities of the same organisms in their biofilm state, as tested by the MBEC assays. CONCLUSIONS: In their biofilm state, gram-negative bacteria are much less susceptible to antibiotics compared to their antibiotic susceptibility in the planktonic state.




This article has been cited by other articles:


Home page
 Clin. Microbiol. Rev.Home page
D. Church, S. Elsayed, O. Reid, B. Winston, and R. Lindsay
Burn Wound Infections
Clin. Microbiol. Rev., April 1, 2006; 19(2): 403 - 434.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Multimed Inc. logo
Copyright © 2004 by Multimed Inc.