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Perit Dial Int 22(6): 649-652 2002
© 2002 International Society for Peritoneal Dialysis
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Peritoneal Dialysis International, Vol 22, Issue 6, 649-652
Copyright © 2002 by International Society for Peritoneal Dialysis

Editorials

Increasing mupirocin resistance of Staphylococcus aureus in CAPD--should it continue to be used as prophylaxis?

JM Conly and S Vas

This editorial summarizes the mechanisms of mupirocin resistance and the conditions that promote its development. While there is increasing evidence that high-level mupirocin resistance is developing during systematic use of mupirocin as prophylaxis against Staphylococcus aureus, the appearance of resistance does not preclude the beneficial effect of regular prophylaxis. Vigilance has to be exercised to notice larger-scale resistance that may require limiting the use of mupirocin.




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