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Perit Dial Int 21(Suppl_3): 236-240 2001
© 2001 International Society for Peritoneal Dialysis
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Peritoneal Dialysis International, Vol 21, Issue Suppl_3, S236-S240
Copyright © 2001 by International Society for Peritoneal Dialysis

Articles

Aggressive therapy of congestive heart failure and associated chronic renal failure with medications and correction of anemia stops or slows the progression of both diseases

DS Silverberg, D Wexler, M Blum, D Sheps, D Schwartz, T Yachnin, R Baruch, J Tchebiner, A Zubkov, M Shaked, S Steinbruch, G Keren, and A Iaina

Department of Nephrology, Tel Aviv Medical Center, Israel. donald@netvision.net.il

The prevalence of congestive heart failure (CHF) is increasing rapidly in the community. We and others have shown that the prevalence and severity of both anemia and chronic renal failure (CRF) increase steadily with increasing severity of CHF. We have also shown that CHF patients may be resistant to standard drug therapy for CHF as long as the associated anemia is not corrected, and that correction of the anemia with subcutaneous erythropoietin and intravenous iron sucrose (Venofer: Vifor International, St. Gallen, Switzerland) may improve both the CHF and CRF and markedly reduce hospitalizations without causing side effects. We report here our experience with correcting anemia in this manner in 126 cases of anemic-resistant CHF patients. As in our previous studies, correction of the anemia improved both CHF and CRF, and reduced hospitalizations. Our studies suggest that correction of even mild anemia in CHF may be an important addition to the treatment of patients with the combination of CHF and CRF.




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Evaluation and long-term prognosis of new-onset, transient, and persistent anemia in ambulatory patients with chronic heart failure.
J. Am. Coll. Cardiol., February 5, 2008; 51(5): 569 - 576.
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