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Perit Dial Int 21(1): 90-92 2001
© 2001 International Society for Peritoneal Dialysis
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Peritoneal Dialysis International, Vol 21, Issue 1, 90-92
Copyright © 2001 by International Society for Peritoneal Dialysis

Articles

Adsorption of erythropoietin and growth hormone to peritoneal dialysis bags and tubing

CH Schroder, LM Swinkels, RE Reddingius, FG Sweep, HL Willems, and LA Monnens

Department of Pediatrics, Wilhelmina Children's University Hospital, Utrecht, The Netherlands. c.h.schroder@wkz.azu.nl

OBJECTIVE: To study the adsorption of erythropoietin and growth hormone to dialysis bags and tubing. DESIGN: In vitro study in which radiolabeled erythropoietin and recombinant human growth hormone were added to small-volume (50- and 250-mL) dialysis bags. Recovery was measured after 15-minute dwells. Experiments were performed in triplicate. SETTING: University hospital. RESULTS: Adsorption of erythropoietin and growth hormone was less than 7%. CONCLUSION: Adsorption of erythropoietin and recombinant human growth hormone to dialysis bags and tubing is minimal. This finding provides another argument in favor of intraperitoneal therapy in pediatric peritoneal dialysis.






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