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REVIEWS AND ORIGINAL ARTICLES |
From the Division of Nephrology, Department of Medicine, Harry S. Truman Memorial Veterans' Hospital and the University of Missouri Health Sciences Center, Columbia, Missouri 65201
A patient with acute pancreatitis was treated with peritoneal dialysis and
had rapid improvement. At frequent intervals during the dialysis, samples of
the patient's blood, urine, and peritoneal fluid were assayed for amylase and
lipase. Calculated renal and peritoneal dialysis clearances of these enzymes
showed that amylase clearance by the kidney was better than that by peritoneal
dialysis; lipase, on the other hand, was more efficiently removed by
peritoneal dialysis than by the kidney. A review of the literature on the use
of peritoneal dialysis in the treatment of acute pancreatitis is followed by
an hypothesis concerning why peritoneal dialysis is so effective in reversing
the course of acute pancreatitis.
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