| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Articles |
Department of Internal Medicine, Karolinska Hospital, Stockholm, Sweden.
OBJECTIVE: To evaluate changes in amount and distribution of body fat in patients treated with continuous ambulatory peritoneal dialysis (CAPD). DESIGN: Prospective study. Computed tomography (CT) and dual energy x-ray absorptiometry (DEXA) were used for determination of body composition at commencement of CAPD, and after a mean of 7.2 months of dialysis treatment. SETTING: CAPD unit at an academic teaching hospital. PATIENTS: The study included 19 consecutive patients who started CAPD during a 15-month time frame. Of these 19 patients, 12 (8 males) with a mean initial age of 60 years completed the study. MAIN OUTCOME MEASURES: Siemens Somatom HiQ (Erlangen, Germany) was used for CT of the abdomen and of the right thigh. Fat and muscle areas were expressed as square centimeters. The proportion of total fat mass was determined by body composition analysis using DEXA (DPX-L densitometer) (Lunar, Madison, WI, U.S.A.) and expressed as percentage of total body weight (FA%). RESULTS: Body weight changed from 67.1 to 68.4 kg (p = 0.20), and the intra-abdominal fat area increased 22.8% (p = 0.02). This increase was predominantly seen in male patients (p = 0.007). The FAT% changed from 27.8% to 30.9% (p = 0.25), without difference between sexes. CONCLUSION: The increase of intra-abdominal fat found in this study may suggest a mechanism by which the established risk for CAPD patients to develop cardiovascular morbidity and mortality may be at least partially explained.
This article has been cited by other articles:
|
|
 |
|
  A.-H. Yang, S.-W. Huang, J.-Y. Chen, J.-K. Lin, and C.-Y. Chen Leptin augments myofibroblastic conversion and fibrogenic activity of human peritoneal mesothelial cells: A functional implication for peritoneal fibrosis Nephrol. Dial. Transplant., March 1, 2007; 22(3): 756 - 762. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Wang, J. Axelsson, L. Nordfors, A. R. Qureshi, C. Avesani, P. Barany, M. Schalling, O. Heimburger, B. Lindholm, and P. Stenvinkel Changes in fat mass after initiation of maintenance dialysis is influenced by the uncoupling protein 2 exon 8 insertion/deletion polymorphism Nephrol. Dial. Transplant., January 1, 2007; 22(1): 196 - 202. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. J. Davies, G. Woodrow, K. Donovan, J. Plum, P. Williams, A. C. Johansson, H.-P. Bosselmann, O. Heimburger, O. Simonsen, A. Davenport, et al. Icodextrin Improves the Fluid Status of Peritoneal Dialysis Patients: Results of a Double-Blind Randomized Controlled Trial J. Am. Soc. Nephrol., September 1, 2003; 14(9): 2338 - 2344. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. STENVINKEL, B. LINDHOLM, F. LÖNNQVIST, K. KATZARSKI, and O. HEIMBÜRGER Increases in Serum Leptin Levels during Peritoneal Dialysis Are Associated with Inflammation and a Decrease in Lean Body Mass J. Am. Soc. Nephrol., July 1, 2000; 11(7): 1303 - 1309. [Abstract] [Full Text]
|
|
|
|
|
|
G. Woodrow, B. Oldroyd, G. Stables, J. Gibson, J. H. Turney, and A. M. Brownjohn Effects of icodextrin in automated peritoneal dialysis on blood pressure and bioelectrical impedance analysis Nephrol. Dial. Transplant., June 1, 2000; 15(6): 862 - 866. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Odamaki, R. Furuya, S. Ohkawa, T. Yoneyama, M. Nishikino, A. Hishida, and H. Kumagai Altered abdominal fat distribution and its association with the serum lipid profile in non-diabetic haemodialysis patients Nephrol. Dial. Transplant., October 1, 1999; 14(10): 2427 - 2432. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
 |
