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Perit Dial Int 12(1): 34-36
1992
© 1992 International Society for Peritoneal Dialysis
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Peritoneal Dialysis International, Vol 12, Issue 1, 34-36
Copyright © 1992 by International Society for Peritoneal Dialysis

Articles

Erythropoietin in continuous ambulatory peritoneal dialysis: experience with subcutaneous administration

G Eisele, GR Bailie, C Clement, and E Wong

Albany College of Pharmacy, New York 12208.

Experience in the use of subcutaneous erythropoietin (EPO) in 32 continuous ambulatory peritoneal dialysis (CAPD) patients is presented. All patients were treated with oral iron supplements. The total and mean +/- SD durations of EPO treatment were 466 weeks and 14.6 +/- 10.1 weeks respectively. Twenty-two patients started treatment with normal or elevated iron stores; 10 had an initial iron saturation less than 20%. The initial hematocrit was 23.8 +/- 3.7%. Thirteen patients reached a steady-state hematocrit by the end of the study period, when the mean +/- SD hematocrit for all 32 patients was 34.1 +/- 3.6%. All patients responded to EPO. The initial dose of EPO was 147.1 +/- 53.8 U/kg/week. Maintenance dose was 72 +/- 36 U/kg/week.






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